منابع مشابه
Aerosolized Antibiotics.
Administration of medications via aerosolization is potentially an ideal strategy to treat airway diseases. This delivery method ensures high concentrations of the medication in the targeted tissues, the airways, with generally lower systemic absorption and systemic adverse effects. Aerosolized antibiotics have been tested as treatment for bacterial infections in patients with cystic fibrosis (...
متن کاملAerosolized antibiotics: current and future.
Aerosolized antibiotic therapy appears to have potential for targeted therapy to the airways and deep lung to prevent VAP in patients at high risk for this disease. The definition of that high-risk population is important if this model is to be successful. We are attempting to define susceptible patients by measuring the volume of airway secretions, which mirrors the inflammation milieu of the ...
متن کاملAerosolized antibiotics for non-cystic fibrosis bronchiectasis.
There are strong data supporting using the use of aerosolized antibiotics for the treatment of Gram-negative infections in patients with cystic fibrosis (CF). The regular use of aerosol tobramycin or colistin can decrease exacerbations of lung disease, decrease bacteria counts, and improve pulmonary function in persons with CF and Pseudomonas aeruginosa airway infection. Bronchiectasis is cause...
متن کاملAerosolized antibiotics in mechanically ventilated patients.
Aerosolized antibiotics are potentially useful in intensive care. At State University of New York at Stony Brook we developed a human model of tracheobronchitis in intubated patients. The model provides daily specimens of airway secretions, allowing serial studies of airway inflammation and testing of therapy modes. The presence of local infection is defined by a unique method of quantified spu...
متن کاملAerosolized antibiotics to treat ventilator-associated pneumonia.
PURPOSE OF REVIEW This review summarizes the recent data on antibiotic aerosolization to treat ventilator-associated pneumonia. RECENT FINDINGS Most studies on antibiotic aerosolization have been case reports or descriptive studies. The results of a recent randomized, placebo-controlled trial indicated that adjunctive use of nebulized antibiotic with intravenous antibiotics to treat purulent ...
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ژورنال
عنوان ژورنال: Respiratory Care
سال: 2015
ISSN: 0020-1324,1943-3654
DOI: 10.4187/respcare.04208